Does Dexedrine Assist with Weight Loss?

  • Off-label use of Dexedrine as a weight loss medication is not recommended by major drug regulatory bodies
  • Current evidence shows Dexedrine provides no long term support for sustained weight loss nor can it be used long term for weight loss
  • Dexedrine has a long list of potential side effects including serious heart problems and self harm
  • The most effective approach to weight loss is eating regular nutritious meals, incorporating regular exercise and approaching any psychological barriers to incorporating healthy changes

What Is Dexedrine?

Dexedrine is the trade name for dextroamphetamine, a prescription psychostimulant medication. Dexedrine is primarily used to treat attention deficit hyperactivity disorder and narcolepsy. However it is sometimes used off-label as a weight loss aid due to its side effect of appetite loss. Chemically, it is relatively similar to the approved weight loss medication phentermine (Duromine).

What Are the Side Effects?

Taking any medication should be taken very seriously. All medicines are known to have side effects. It is never known how your body or mind will deal with these medicines until it is consumed or applied. Side effects of Dexedrine include:

  • Fast, pounding, or irregular heartbeat;
  • Sweating;
  • Dilated pupils;
  • Abnormally excited mood;
  • Irritability;
  • Restlessness, difficulty falling sleeping or staying asleep;
  • Hostility, aggression, or anxiety;
  • Loss of appetite;
  • Loss of coordination;
  • Uncontrollable movement of a part of the body;
  • Changes in libido;
  • Flushed skin;
  • Vomiting;
  • Stomach pain;
  • Thinking about harming or killing oneself or others or planning or trying to do so

Overusing dextroamphetamine may also cause serious heart problems or sudden death.

Dextroamphetamine & Weight Loss

This is a controversial short-term use drug. As mentioned previously, Dexedrine is sometimes prescribed as an appetite suppressant by some doctors - however it is not approved as a weight loss medication in Australia. Furthermore, off-label use as a weight loss medication is not recommended by major drug regulatory bodies.

When Dexedrine is prescribed for suppressing appetite however, it is typically only for a short period of time lasting no more than 12 weeks. This is in part because the longer you take Dexedrine the more your body builds a tolerance to its effects, and the side effect of appetite loss diminishes. Furthermore, because Dexedrine is habit forming, taking it as a weight loss aid for longer than 12 weeks increases your risk of developing an addiction to this medication (Wittman, 2022).

There are many drugs on the market used for other ailments that can also activate or accelerate weight loss. However, taking the step to use such a drug for its unintended purpose is a significant consideration to say the least.

When it is used in the medical community, it has to be stressed that once you stop taking Dexedrine, your appetite will return. If you have not learned any healthy habits or positive change, your weight will simply return when you cease the medication and return to your normal habits.

Our LifeShape Clinical Recommendations for Weight Loss

When choosing a weight loss prescription or program it can be tempting to focus on achieving the initial weight loss, however it is also important to look at what you want to achieve and what you can sustain and afford in the long term.

The LifeShape clinic recommendations for weight loss are focused on utilising the combined expertise of our team of health care professionals that include Dietitians, Exercise Physiologist, Psychologists and Medical Doctors so that we can help individualise a plan to help you achieve your weight loss goals while building sustainable long term changes that add to your health such as eating regular nutritious meals, incorporating regular exercise and approaching any psychological barriers to incorporating healthy changes.


  • Wittman, L. (2022)


Tap to call us at 1800 567 348

Fill in your details below and our team will be in contact shortly to answer your questions and get you started.

"*" indicates required fields

How we're responding to COVID-19...
Find out more>
Our Disclaimer: All client testimonials are genuine accounts of experiences on the LifeShape program. Due to the personalised nature of the LifeShape program, results may vary based on an individual’s compliance, motivation and personal history.

This 30 minutes

could save your life.

Just $50* - May Only.

Being overweight is a precurser to heart disease and a DEXA Scan is the perfect starting point to get a picture of your belly fat, and your health risk.

*Milton Clinic only

linkedin facebook pinterest youtube rss twitter instagram facebook-blank rss-blank linkedin-blank pinterest youtube twitter instagram